Non-simultaneous bilateral hip fracture. A retrospective cohort study
DOI:
https://doi.org/10.1016/j.rccot.2017.06.005Keywords:
hip fracture, contralateral, fracture, epidemiology, osteoporosisAbstract
Background and aim: After a first hip fracture, the contralateral hip can also get fractured. The characteristics of this second hip fracture are determined and its differences with the first one are evaluated.
Materials and methods: Retrospective cohort study was conducted that included patients older than 50 years old with a hip fracture. Patients were excluded if they had pathological fractures, high-energy fractures, peri-prosthetic fractures, bilateral simultaneous fracture, a history of ipsilateral hip fracture, and ipsilateral simultaneous femur fracture. A total of 610 patients with a fracture over a 10-year period (2005-2014) were eligible at the institution. They were divided in two groups: first and second hip fracture. The incidence of non-simultaneous bilateral hip fracture was calculated and for each group, the demographic variables, complications, comorbidities, and mortality were recorded.
Results: The incidence of non-simultaneous bilateral hip fracture was 8.0% (n = 49). The mean time between the first and second fracture was 2.3 years. Patients were, on average, 85 yearsold when they fractured the second time, and 6 years older than for the first fracture. Of the 49 patients included, 77.6% were women (n = 38), with a ratio of 3.5 to 1 in relation to men. There were more medical complications for the second fracture, as well as a higher prevalence of dementia and diabetes. The 3 months mortality rate was higher for the second fracture: 10.2% vs 6.9%, with a RR=1.46 (95% CI: 0.6-3.6) (p=.39).
Discussion: The second fracture occurs several years after the first one, is more frequent in women, and could be associated with more complications and higher mortality.
Level of evidence: II.
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References
Centers for Disease Control and Prevention. Incidence and costs to Medicare of fractures among Medicare beneficiaries aged > 65 years-United States, July 1991-June 1992. Morb Mortal Wkly Rep. 1996;45:877-83.
Khaltaev N, Pfleger B, Lidgren L. (2003, October 27). Musculoskeletal conditions affect millions. Disponible en: http://www.who.int/mediacentre/news/releases/2003/pr81/en/.
Farahmand BY, Michaelsson K, Ahlbom A, Ljunghall S, Baron JA, Swedish Hip Fracture Study Group. Survival after hip fracture. Osteoporos Int. 2005;16:1583-90. https://doi.org/10.1007/s00198-005-2024-z
Haentjens P, Magaziner J, Colon-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, et al. Meta-analysis: excess mortality after hip fracture among older women and men. Ann Inter Med. 2010;152:380-90. https://doi.org/10.7326/0003-4819-152-6-201003160-00008
Martínez Rondanelli A. Factores de riesgo asociados a la mortalidad a un año en pacientes con fracturas de cadera. Rev Colomb Ortop Traumatol. 2010;24:11-8.
Berry SD, Samelson EJ, Hannan MT, McLean RR, Lu M, Cupples LA, et al. Second hip fracture in older men and women: the Framingham Study. Arch Intern Med. 2007;167:1971-6. https://doi.org/10.1001/archinte.167.18.1971
Kaper BP, Mayor MB. Incidence of bilateral proximal femoral fractures in a tertiary care center. Orthopedics. 2001;24: 571-4. https://doi.org/10.3928/0147-7447-20010601-14
Lonnroos E, Kautiainen H, Karppi P, Hartikainen S, Kiviranta I, Sulkava R. Incidence of second hip fractures. A populationbased study. Osteoporos Int. 2007;18:1279-85. https://doi.org/10.1007/s00198-007-0375-3
Melton LJ 3rd, Kearns AE, Atkinson EJ, Bolander ME, Achenbach SJ, Huddleston JM, et al. Secular trends in hip fracture incidence and ecurrence. Osteoporos Int. 2009;20: 687-94. https://doi.org/10.1007/s00198-008-0742-8
Van der Steenhoven TJ, Staffhorst B, Van de Velde S, Nelissen RG, Verhofstad MH. Complications and institutionalization are almost doubled after second hip fractures surgery in the elderly patient. J Orthop Trauma. 2015;29:e103-8. https://doi.org/10.1097/BOT.0000000000000233
Ryg J, Rejnmark L, Overgaard S, Brixen K, Vestergaard P. Hip fracture patients at risk of second hip fracture: a nationwide population-based cohort study of 169.145 cases during 1977- 2001. J Bone Miner Res. 2009;24:1299-307. https://doi.org/10.1359/jbmr.090207
Vochteloo AJ, Borger van der Burg BL, Roling MA, van Leeuwen DH, van den Berg P, Niggebrugge AH, et al. Contralateral hip fractures and other osteoporosis-related fractures in hip fractures patients: incidence and risk factors. An observational cohort study of 1229 patients. Arch Orthop Trauma Surg. 2012;132:1191-7. https://doi.org/10.1007/s00402-012-1520-9
Ruan WD, Wang P, Ma XL, Ge RP, Zhou XH. Analysis on the risk factors of second fracture in osteoporosis-related fractures. Chin J Traumatol. 2011;14:74-8.
Mitani S, Shimizu M, Abo M, Hagino H, Kurozawa Y. Risk factors for second hip fractures among elderly patients. J Orthop Sci. 2010;15:192-7. https://doi.org/10.1007/s00776-009-1440-x
Chapurlat RD, Bauer DC, Nevitt M, Stone K, Cummings SR. Incidence and risk factors for a second hip fracture in elderly women: The Study of Osteoporotic. Osteoporos Int. 2003;14:130-6. https://doi.org/10.1007/s00198-002-1327-6
Yamanashi A, Yamazaki K, Kanamori M, Mochizuki K, Okamoto S, Koide Y, et al. Assessment of risk factors for second hip fractures in Japanese elderly. Osteoporos Int. 2005;16: 1239-46. https://doi.org/10.1007/s00198-005-1835-2
Kim SM, Moon YW, Lim SJ, Yoon BK, Min YK, Lee DY, et al. Prediction of survival, second fracture, and functional recovery following the first hip fracture surgery in elderly patients. Bone. 2012;50:1343-50. https://doi.org/10.1016/j.bone.2012.02.633
Pearce EO, Redfern DJ, Sinha M, Edge AJ. Outcome following a second hip fracture. Injury. 2003;34:518-21. https://doi.org/10.1016/S0020-1383(02)00282-6
McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, et al., Hip Intervention Program Study Group. Effect of risedronate on the risk of hip fracture in elderly women. N Engl J Med. 2001;344:333-40. https://doi.org/10.1056/NEJM200102013440503
Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005;293:2257-64. https://doi.org/10.1001/jama.293.18.2257
Holt G, Smith R, Duncan K, Hutchison JD, Gregori A, Reid D. Outcome after sequential hip fracture in the elderly. J Bone Joint Surg Am. 2012;94:1801-8. https://doi.org/10.2106/JBJS.J.01539
Sawalha S, Parker MJ. Characteristics and outcome in patients sustaining a second contralateral fracture of the hip. J Bone Joint Surg Br. 2012;94:102-6. https://doi.org/10.1302/0301-620X.94B1.27983
Dindo D, Demartines N, Clavien PA. Classification of surgical complications; a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205-13. https://doi.org/10.1097/01.sla.0000133083.54934.ae
Omsland TK, Holvik K, Meyer HE, Center JR, Emaus N, Tell GS, et al. Hip fractures in Norway 1999-2008: time trends in total incidence and second hip fracture rates. A NOREPOS study. Eur J Epidemiol. 2012;27:807-14. https://doi.org/10.1007/s10654-012-9711-9
Kok LM, Can der Steenhoven TJ, Nelissen RG. A retrospective analysis of bilateral fractures over sixteen years: Localization and variation in treatment of second hip fractures. Int Orthop. 2011;35:1545-51. https://doi.org/10.1007/s00264-010-1176-4
Gaumetou E, Zilber S, Hernigou P. Non-simultaneous bilateral hip fracture: epidemiologic study of 241 hip fractures. Orthop Traumatol Surg Res. 2011;97:22-7. https://doi.org/10.1016/j.otsr.2010.07.011
Kaukonen JP, Lüthje P, Nurmi-Lüthje I, Kataja M, Naboulsi H. Second hip fracture and patientsmedication ' after the first hip fracture: a follow up of 221 hip fracture patients in Finland. Arch Gerontol Geriatr. 2001;52:185-9. https://doi.org/10.1016/j.archger.2010.03.015
Shabat S, Gepstein R, Mann G, Kish B, Fredman B, Nyska M. The second hip fracture - an analysis of 84 elderly patients. J Orthop Trauma. 2003;17:613-7. https://doi.org/10.1097/00005131-200310000-00003
Rodaro E, Pasqualini M, Iona LG, Di Benedetto P. Functional recovery after a second hip fracture. Eura Medicophys. 2004;40:179-83.
Hagino H, Sawaguchi T, Eno N, Ito Y, Nakano T, Watanabe Y. The risk if a second hip fracture in patients after their first hip fracture. Calcif Tissue Int. 2012;90:14-21. https://doi.org/10.1007/s00223-011-9545-6
Huybrechts KF, Ishak KJ, Caro JJ. Assessment of compliance with osteoporosis treatment and its consequences in a managed care population. Bone. 2006;38:922-8. https://doi.org/10.1016/j.bone.2005.10.022
Ip D, Ip FK. Elderly patients with two episodes of fragility hip fractures form a special subgroup. J Orthop Surg (Hong Kong). 2006;14:245-8.
https://doi.org/10.1177/230949900601400303
Curtis JR, Arora T, Matthews RS, Taylor A, Becker DJ, ColonEmeric C, et al. Is withholding osteoporosis medication after fracture sometimes rational? A comparison of the risk for second fracture versus death. J Am Med Dir Assoc. 2010;11: 584-91. https://doi.org/10.1016/j.jamda.2009.12.004
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