Ultrasound guided platelet-rich plasma injection for the treatment of rotator cuff tendinopathy: changing the concept of palliative pain management to regenerative shoulder therapy
DOI:
https://doi.org/10.1016/j.rccot.2020.04.015Keywords:
plasma rich in growth factors, chronic shoulder pain, rotator cuff, ultrasound-guided injectionAbstract
Background: Plasma rich in growth factors (PRGF) is a natural concentrate of autologous blood polypeptides already used in several fields of medicine because of its potential to enhance tissue regeneration. The aim of this study is to explore this novel approach to treat rotator cuff injuries of the shoulder.
Materials and methods: A case series of patients with chronic pain of the shoulder and failed conservative pharmacological management were treated with ultrasound-guided intra-articular injections of the shoulder with PRGF. The procedure consisted of two ultrasound-guided injections of PRGF in a 6 week interval, in each component of the rotator cuff depending on the findings of the previous ultrasound or the MRI study of the shoulder. Patients were clinically prospectively evaluated, before and one month after, the second injection of PRGF, and then at a 6 months follow-up.
Results: A significant improvement in the clinical evaluation scores (VAS score for pain intensity and Macnab criteria for functional recovery) was obtained from the initial evaluation to the end of the 6 months follow-up.
Discussion: The results indicate that the treatment with PRGF injections is safe and has the potential to reduce pain and improve shoulder function, and the quality of life in patients with rotator cuff injury.
Evidence Level: IV
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References
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